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Last updated: 2016/10/23
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HP purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00003240-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human HP protein.
  • Immunogen:
  • HP (AAH70299.1, 1 a.a. ~ 281 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of HP expression in transfected 293T cell line (H00003240-T01) by HP MaxPab polyclonal antibody.

    Lane 1: HP transfected lysate(30.91 KDa).
    Lane 2: Non-transfected lysate.
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  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3240
  • Gene Name:
  • HP
  • Gene Alias:
  • BP,HP2-ALPHA-2,HPA1S,MGC111141
  • Gene Description:
  • haptoglobin
  • Gene Summary:
  • This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • binding peptide,haptoglobin alpha(1S)-beta,haptoglobin alpha(2FS)-beta,haptoglobin, alpha polypeptide,haptoglobin, beta polypeptide
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