HOXD4 monoclonal antibody (M01), clone 1H7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant HOXD4.
Immunogen
HOXD4 (NP_055436.2, 1 a.a. ~ 62 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQPF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (32.56 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged HOXD4 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — HOXD4
Entrez GeneID
3233GeneBank Accession#
NM_014621Protein Accession#
NP_055436.2Gene Name
HOXD4
Gene Alias
HHO.C13, HOX-5.1, HOX4, HOX4B, Hox-4.2
Gene Description
homeobox D4
Omim ID
142981Gene Ontology
HyperlinkGene Summary
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq
Other Designations
Hox-4.2, mouse, homolog of homeo box X|homeo box D4|homeobox protein Hox-D4
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Interactome
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Disease
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