HOXB9 monoclonal antibody (M01), clone 3C8
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a full-length recombinant HOXB9.
Immunogen
HOXB9 (NP_076922.1, 65 a.a. ~ 163 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEG
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
HOXB9 monoclonal antibody (M01), clone 3C8 Western Blot analysis of HOXB9 expression in HepG2 ( Cat # L019V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged HOXB9 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — HOXB9
Entrez GeneID
3219GeneBank Accession#
NM_024017Protein Accession#
NP_076922.1Gene Name
HOXB9
Gene Alias
HOX-2.5, HOX2, HOX2E
Gene Description
homeobox B9
Omim ID
142964Gene Ontology
HyperlinkGene Summary
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq
Other Designations
homeo box 2E|homeo box B9
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Interactomes
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Diseases
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Publication Reference
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Elevated HOXB9 expression promotes differentiation and predicts a favourable outcome in colon adenocarcinoma patients.
Zhan J, Niu M, Wang P, Zhu X, Li S, Song J, He H, Wang Y, Xue L, Fang W, Zhang H.
British Journal of Cancer 2014 Aug; 111(5):883.
Application:WB-Ce, WB-Tr, Human, Mouse, SW480, SW620, HCT116, RKO, LST, SW1116, HT29, T47D, Hs578T, SUM159 cells, Colon, Intestine, Duodenum.
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Elevated HOXB9 expression promotes differentiation and predicts a favourable outcome in colon adenocarcinoma patients.
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