HOXB8 (Human) Recombinant Protein (P01)
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More Files
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Specifications
Product Description
Human HOXB8 full-length ORF (BAC04730.1, 1 a.a. - 243 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQNPCAVACHGDPDNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFHSSKCEQEELEKQKLERAPEAADEGDAQKGDKK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
54.1
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HOXB8
Entrez GeneID
3218GeneBank Accession#
AK096222.1Protein Accession#
BAC04730.1Gene Name
HOXB8
Gene Alias
HOX2, HOX2D, Hox-2.4
Gene Description
homeobox B8
Omim ID
142963Gene Ontology
HyperlinkGene Summary
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. [provided by RefSeq
Other Designations
homeo box 2D|homeo box B8
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