HMGB3 (Human) Recombinant Protein (P01)
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More Files
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Specifications
Product Description
Human HMGB3 full-length ORF ( NP_005333.2, 1 a.a. - 200 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKFDEMAKADKVRYDREMKDYGPAKGGKKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFDGAKGPAKVARKKVEEEDEEEEEEEEEEEEEEDE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
49.4
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HMGB3
Entrez GeneID
3149GeneBank Accession#
NM_005342.2Protein Accession#
NP_005333.2Gene Name
HMGB3
Gene Alias
HMG2A, HMG4, MGC90319
Gene Description
high-mobility group box 3
Omim ID
300193Gene Ontology
HyperlinkGene Summary
HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]).[supplied by OMIM
Other Designations
OTTHUMP00000025865|high-mobility group (nonhistone chromosomal) protein 4|non-histone chromosomal protein
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