HMBS (Human) Matched Antibody Pair
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Sandwich ELISA detection sensitivity ranging from 10 ng/ml to 100 ng/ml.
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human HMBS.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91%); Rat (91%)
Quality Control Testing
Standard curve using recombinant protein ( H00003145-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 10 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-HMBS (100 ug)
2. Detection antibody: mouse monoclonal anti-HMBS, IgG2a Kappa (20 ug)
*Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
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Gene Info — HMBS
Entrez GeneID
3145Gene Name
HMBS
Gene Alias
PBG-D, PBGD, UPS
Gene Description
hydroxymethylbilane synthase
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
porphobilinogen deaminase|pre-uroporphyrinogen synthase|uroporphyrinogen I synthase|uroporphyrinogen I synthetase
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Interactome
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Pathway
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Disease
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