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HLA-F Pre-design Chimera RNAi

  • Catalog # : H00003134-R02
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Homo sapiens major histocompatibility complex, class I, F (HLA-F), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_018950
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 3134
  • Gene Name:
  • HLA-F
  • Gene Alias:
  • CDA12,HLA-5.4,HLA-CDA12,HLAF
  • Gene Description:
  • major histocompatibility complex, class I, F
  • Gene Summary:
  • This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. [provided by RefSeq
  • Other Designations:
  • HLA class I molecule,MHC class I antigen,MHC class Ib antigen,OTTHUMP00000109209,OTTHUMP00000109210,OTTHUMP00000109211,leukocyte antigen F
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