HLA-E MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of HLA-E expression in transfected 293T cell line (H00003133-T02) by HLA-E MaxPab polyclonal antibody.
Lane 1: HLA-E transfected lysate(40.2 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of HLA-E transfected lysate using anti-HLA-E MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with HLA-E MaxPab mouse polyclonal antibody (B01) (H00003133-B01).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human HLA-E protein.
Immunogen
HLA-E (AAH02578.1, 1 a.a. ~ 358 a.a) full-length human protein.
Sequence
MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELGPDRRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSESHSL
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69); Rat (62)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of HLA-E expression in transfected 293T cell line (H00003133-T02) by HLA-E MaxPab polyclonal antibody.
Lane 1: HLA-E transfected lysate(40.2 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of HLA-E transfected lysate using anti-HLA-E MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with HLA-E MaxPab mouse polyclonal antibody (B01) (H00003133-B01). -
Gene Info — HLA-E
Entrez GeneID
3133GeneBank Accession#
BC002578Protein Accession#
AAH02578.1Gene Name
HLA-E
Gene Alias
DKFZp686P19218, EA1.2, EA2.1, HLA-6.2, MHC, QA1
Gene Description
major histocompatibility complex, class I, E
Omim ID
143010Gene Ontology
HyperlinkGene Summary
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq
Other Designations
HLA class I histocompatibility antigen, E alpha chain|MHC HLA-E alpha-1|MHC HLA-E alpha-2.1|MHC class I antigen|OTTHUMP00000029214|lymphocyte antigen
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Interactome
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Pathway
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Disease
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