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HLA-DQB1 MaxPab mouse polyclonal antibody (B01)MaxPab

  • Catalog # : H00003119-B01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human HLA-DQB1 protein.
  • Immunogen:
  • HLA-DQB1 (AAH12106, 1 a.a. ~ 261 a.a) full-length human protein.
  • Sequence:
  • MSWKKALRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKGLLH
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
  • Applications
  • Flow Cytometry
  • Flow Cytometry enlargeenlarge this image
  • FACS analysis of negative control 293 cells (Black) and HLA-DQB1 expressing 293 cells (Green) using HLA-DQB1 purified MaxPab mouse polyclonal antibody.
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • HLA-DQB1 MaxPab polyclonal antibody. Western Blot analysis of HLA-DQB1 expression in human pancreas.
  • PDF DownloadProtocol Download
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of HLA-DQB1 expression in transfected 293T cell line (H00003119-T01) by HLA-DQB1 MaxPab polyclonal antibody.

    Lane 1: HLA-DQB1 transfected lysate(28.71 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3119
  • Gene Name:
  • HLA-DQB1
  • Gene Alias:
  • CELIAC1,HLA-DQB,IDDM1
  • Gene Description:
  • major histocompatibility complex, class II, DQ beta 1
  • Gene Summary:
  • HLA-DQB1 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq
  • Other Designations:
  • MHC DQ beta,MHC class II DQ beta chain,MHC class II HLA-DQ beta glycoprotein,MHC class II antigen DQB1,MHC class II antigen HLA-DQ-beta-1,MHC class2 antigen,OTTHUMP00000178570,lymphocyte antigen,major histocompatibility complex class II beta
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