HLA-DPB1 293T Cell Transient Overexpression Lysate(Denatured)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Transfected Cell Line
293T
Plasmid
pCMV-HLA-DPB1 full-length
Host
Human
Theoretical MW (kDa)
29.2
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-HLA-DPB1 antibody (H00003115-B01) by Western Blots.
SDS-PAGE Gel
HLA-DPB1 transfected lysate
Western Blot
Lane 1: HLA-DPB1 transfected lysate ( 29.2 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot
-
Gene Info — HLA-DPB1
Entrez GeneID
3115GeneBank Accession#
NM_002121Protein Accession#
NP_002112Gene Name
HLA-DPB1
Gene Alias
DPB1, HLA-DP1B
Gene Description
major histocompatibility complex, class II, DP beta 1
Omim ID
142858Gene Ontology
HyperlinkGene Summary
HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq
Other Designations
HLA DP14-beta chain|HLA-DP histocompatibility type, beta-1 subunit|MHC HLA DPB1|MHC class II HLA-DP-beta|MHC class II HLA-DP-beta-1|MHC class II HLA-DRB1|MHC class II antigen DP beta 1 chain|MHC class II antigen DPbeta1|MHC class II antigen beta chain|OTT
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com