HLA-DOA rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human HLA-DOA peptide using ARM Technology.
Immunogen
A synthetic peptide of human HLA-DOA is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human HLA-DOA peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — HLA-DOA
Entrez GeneID
3111GeneBank Accession#
HLA-DOAGene Name
HLA-DOA
Gene Alias
HLA-DNA, HLA-DZA, HLADZ
Gene Description
major histocompatibility complex, class II, DO alpha
Omim ID
142930Gene Ontology
HyperlinkGene Summary
HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq
Other Designations
HLA-D0-alpha|MHC class II antigen|OTTHUMP00000029303|lymphocyte antigen|major histocompatibility complex, class II, DN alpha
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