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Last updated: 2017/7/23

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HLA-DOA rabbit monoclonal antibody

  • Catalog # : H00003111-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human HLA-DOA peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human HLA-DOA is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human HLA-DOA peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3111
  • Gene Name:
  • HLA-DOA
  • Gene Alias:
  • HLA-DNA,HLA-DZA,HLADZ
  • Gene Description:
  • major histocompatibility complex, class II, DO alpha
  • Gene Summary:
  • HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq
  • Other Designations:
  • HLA-D0-alpha,MHC class II antigen,OTTHUMP00000029303,lymphocyte antigen,major histocompatibility complex, class II, DN alpha
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