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Last updated: 2017/10/15

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HLA-DMA 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00003108-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-HLA-DMA full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 29.2
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-HLA-DMA antibody (H00003108-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00003108-T01
    HLA-DMA transfected lysate
    Western Blot
    QC Testing of H00003108-T01
    Lane 1: HLA-DMA transfected lysate ( 29.2 KDa).
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 3108
  • Gene Name:
  • HLA-DMA
  • Gene Alias:
  • D6S222E,DMA,HLADM,RING6
  • Gene Description:
  • major histocompatibility complex, class II, DM alpha
  • Gene Summary:
  • HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000029242,OTTHUMP00000062997,class II histocompatibility antigen, M alpha chain
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