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Last updated: 2016/10/23
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HLA-C MaxPab rabbit polyclonal antibody (D01)MaxPab

  • Catalog # : H00003107-D01
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human HLA-C protein.
  • Immunogen:
  • HLA-C (AAH02463.1, 1 a.a. ~ 366 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of HLA-C expression in transfected 293T cell line (H00003107-T01) by HLA-C MaxPab polyclonal antibody.

    Lane 1: HLA-C transfected lysate(40.80 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation of HLA-C transfected lysate using anti-HLA-C MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with HLA-C purified MaxPab mouse polyclonal antibody (B01P) (H00003107-B01P).
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3107
  • Gene Name:
  • HLA-C
  • Gene Alias:
  • D6S204,FLJ27082,HLA-Cw,HLA-Cw12,HLA-JY3,HLC-C,PSORS1
  • Gene Description:
  • major histocompatibility complex, class I, C
  • Gene Summary:
  • HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described [provided by RefSeq
  • Other Designations:
  • HLA class I antigen,HLA class I heavy chain,HLA class I histocompatibility antigen, C alpha chain,HLA-C (Cw*1201),HLA-Cw*050x,MHC class I HLA-C,MHC class I HLA-Cw*0803,MHC class I antigen HLA-C,MHC class I antigen heavy chain HLA-C,MHC class I protein HLA
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