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Last updated: 2016/12/4

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HIP2 Pre-design Chimera RNAi

  • Catalog # : H00003093-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens huntingtin interacting protein 2 (HIP2), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_005339
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 3093
  • Gene Name:
  • UBE2K
  • Gene Alias:
  • DKFZp564C1216,DKFZp686J24237,E2-25K,HIP2,HYPG,LIG
  • Gene Description:
  • ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
  • Gene Summary:
  • The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • huntingtin interacting protein 2,ubiquitin carrier protein,ubiquitin-conjugating enzyme E2-25 KDA,ubiquitin-conjugating enzyme E2-25K,ubiquitin-protein ligase
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