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Last updated: 2017/4/23

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HIP2 (Human) Recombinant Protein (P02)

  • Catalog # : H00003093-P02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human HIP2 full-length ORF ( NP_005330.1, 1 a.a. - 200 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • MANIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKKIENLCAMGFDRNAVIVALSSKSWDVETATELLLSN
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 48.8
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00003093-P02
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 3093
  • Gene Name:
  • UBE2K
  • Gene Alias:
  • DKFZp564C1216,DKFZp686J24237,E2-25K,HIP2,HYPG,LIG
  • Gene Description:
  • ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
  • Gene Summary:
  • The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • huntingtin interacting protein 2,ubiquitin carrier protein,ubiquitin-conjugating enzyme E2-25 KDA,ubiquitin-conjugating enzyme E2-25K,ubiquitin-protein ligase
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