UBE2K monoclonal antibody (M13), clone 1D10
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant UBE2K.
Immunogen
UBE2K (-, 1 a.a. ~ 40 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MLAMSPPAADSYPPPPPPLRPPPPPPPLPPPPPPSAIQT*
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (30.40 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged UBE2K is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — UBE2K
Entrez GeneID
3093GeneBank Accession#
BC006419Protein Accession#
-Gene Name
UBE2K
Gene Alias
DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG
Gene Description
ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
Omim ID
602846Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
huntingtin interacting protein 2|ubiquitin carrier protein|ubiquitin-conjugating enzyme E2-25 KDA|ubiquitin-conjugating enzyme E2-25K|ubiquitin-protein ligase
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Interactome
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Pathway
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