HIP1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-HIP1 full-length
Host
Human
Theoretical MW (kDa)
114.18
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-HIP1 antibody (H00003092-B01) by Western Blots.
SDS-PAGE Gel
HIP1 transfected lysate.
Western Blot
Lane 1: HIP1 transfected lysate ( 114.18 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — HIP1
Entrez GeneID
3092GeneBank Accession#
NM_005338.4Protein Accession#
NP_005329.3Gene Name
HIP1
Gene Alias
ILWEQ, MGC126506
Gene Description
huntingtin interacting protein 1
Gene Ontology
HyperlinkGene Summary
The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. An alternative splice variant of this gene has been described but its full length sequence has not been determined. [provided by RefSeq
Other Designations
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Interactome
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Disease
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