NRG1 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
NRG1 MaxPab rabbit polyclonal antibody. Western Blot analysis of NRG1 expression in human placenta.
Western Blot (Transfected lysate)
Western Blot analysis of NRG1 expression in transfected 293T cell line (H00003084-T03) by NRG1 MaxPab polyclonal antibody.
Lane 1: NRG1 transfected lysate(26.10 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of NRG1 transfected lysate using anti-NRG1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with NRG1 purified MaxPab mouse polyclonal antibody (B02P) (H00003084-B02P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human NRG1 protein.
Immunogen
NRG1 (NP_039252.1, 1 a.a. ~ 241 a.a) full-length human protein.
Sequence
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPQLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYSTSTPFLSLPE
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
NRG1 MaxPab rabbit polyclonal antibody. Western Blot analysis of NRG1 expression in human placenta.Western Blot (Transfected lysate)
Western Blot analysis of NRG1 expression in transfected 293T cell line (H00003084-T03) by NRG1 MaxPab polyclonal antibody.
Lane 1: NRG1 transfected lysate(26.10 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of NRG1 transfected lysate using anti-NRG1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with NRG1 purified MaxPab mouse polyclonal antibody (B02P) (H00003084-B02P). -
Gene Info — NRG1
Entrez GeneID
3084GeneBank Accession#
NM_013958.1Protein Accession#
NP_039252.1Gene Name
NRG1
Gene Alias
ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, NDF, SMDF
Gene Description
neuregulin 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). [provided by RefSeq
Other Designations
glial growth factor|heregulin, alpha (45kD, ERBB2 p185-activator)|neu differentiation factor|neuregulin 1 isoform HRG-gamma|sensory and motor neuron derived factor
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Interactome
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Pathway
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Disease
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