HGD (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human HGD partial ORF ( NP_000178, 377 a.a. - 445 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
CFEKASKVKLAPERIADGTMAFMFESSLSLAVTKWGLKASRCLDENYHKCWEPLKSHFTPNSRNPAEPN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
33.33
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HGD
Entrez GeneID
3081GeneBank Accession#
NM_000187Protein Accession#
NP_000178Gene Name
HGD
Gene Alias
AKU, HGO
Gene Description
homogentisate 1,2-dioxygenase (homogentisate oxidase)
Gene Ontology
HyperlinkGene Summary
Homogentisate 1,2-dioxygenase (HGD) gene mutations are the molecular cause of alkaptonuria, a rare hereditary disorder of the phenylalanine catabolism. The highest expression of HGD is in the prostate, small intestine, colon, and liver. The HGD gene contains 14 exons. Conflicting reports have placed the gene at 3q2, 3q13.3-q21, 3q21-q24, 3q21-q23, or 3q25-q26. [provided by RefSeq
Other Designations
homogentisate 1,2-dioxygenase|homogentisicase
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Interactome
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Pathway
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