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Last updated: 2017/12/10

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HFE (Human) Recombinant Protein (Q01)

  • Catalog # : H00003077-Q01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human HFE partial ORF ( NP_000401, 115 a.a. - 205 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQ
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 35.75
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00003077-Q01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 3077
  • Gene Name:
  • HFE
  • Gene Alias:
  • HFE1,HH,HLA-H,MGC103790,dJ221C16.10.1
  • Gene Description:
  • hemochromatosis
  • Gene Summary:
  • The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq
  • Other Designations:
  • MHC class I-like protein HFE,hemochromatosis protein,hereditary hemochromatosis protein HLA-H
  • Related Disease
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