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Last updated: 2016/12/4

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HEXA Pre-design Chimera RNAi

  • Catalog # : H00003073-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens hexosaminidase A (alpha polypeptide) (HEXA), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000520
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 3073
  • Gene Name:
  • HEXA
  • Gene Alias:
  • MGC99608,TSD
  • Gene Description:
  • hexosaminidase A (alpha polypeptide)
  • Gene Summary:
  • This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq
  • Other Designations:
  • GM2 gangliosidosis,N-acetyl-beta-glucosaminidase,Tay Sachs disease,beta-N-acetylhexosaminidase,hexosaminidase A
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