HEXA (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of HEXA transfected lysate using rabbit polyclonal anti-HEXA and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-HEXA.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of HEXA transfected lysate using rabbit polyclonal anti-HEXA and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-HEXA.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-HEXA (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-HEXA (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — HEXA
Entrez GeneID
3073Gene Name
HEXA
Gene Alias
MGC99608, TSD
Gene Description
hexosaminidase A (alpha polypeptide)
Gene Ontology
HyperlinkGene Summary
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq
Other Designations
GM2 gangliosidosis|N-acetyl-beta-glucosaminidase|Tay Sachs disease|beta-N-acetylhexosaminidase|hexosaminidase A
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Interactome
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Pathway
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Disease
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