HDAC1 (Human) Recombinant Protein (Q01)

Catalog # H00003065-Q01

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Size:25 ug
Price: USD $ 510.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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  • Specification

    Product Description

    Human HDAC1 partial ORF ( NP_004955, 28 a.a. - 137 a.a.) recombinant protein with GST-tag at N-terminal.

    Sequence

    HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAG

    Host

    Wheat Germ (in vitro)

    Theoretical MW (kDa)

    37.84

    Interspecies Antigen Sequence

    Mouse (100); Rat (100)

    Preparation Method

    in vitro wheat germ expression system

    Purification

    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue.

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

    Note

    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — HDAC1

    Entrez GeneID

    3065

    GeneBank Accession#

    NM_004964

    Protein Accession#

    NP_004955

    Gene Name

    HDAC1

    Gene Alias

    DKFZp686H12203, GON-10, HD1, RPD3, RPD3L1

    Gene Description

    histone deacetylase 1

    Omim ID

    601241

    Gene Ontology

    Hyperlink

    Gene Summary

    Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq

    Other Designations

    OTTHUMP00000008745|reduced potassium dependency, yeast homolog-like 1

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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