HBG1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human HBG1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTAVASALSSRYH
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — HBG1
Entrez GeneID
3047GeneBank Accession#
NM_000559.2Protein Accession#
NP_000550.2Gene Name
HBG1
Gene Alias
HBGA, HBGR, HSGGL1, PRO2979
Gene Description
hemoglobin, gamma A
Omim ID
142200Gene Ontology
HyperlinkGene Summary
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq
Other Designations
A-gamma globin|gamma A hemoglobin|gamma globin|hemoglobin gamma-a chain|hemoglobin, gamma, regulator of
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