HBG1 (Human) Recombinant Protein (P02)
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More Files
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Specification
Product Description
Human HBG1 full-length ORF ( AAH10914, 1 a.a. - 147 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVASALSSRYH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
41.91
Interspecies Antigen Sequence
Rat (75)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HBG1
Entrez GeneID
3047GeneBank Accession#
BC010914Protein Accession#
AAH10914Gene Name
HBG1
Gene Alias
HBGA, HBGR, HSGGL1, PRO2979
Gene Description
hemoglobin, gamma A
Omim ID
142200Gene Ontology
HyperlinkGene Summary
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq
Other Designations
A-gamma globin|gamma A hemoglobin|gamma globin|hemoglobin gamma-a chain|hemoglobin, gamma, regulator of
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Interactome
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