HBG1 monoclonal antibody (M02), clone M2
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of HBG1 expression in transfected 293T cell line by HBG1 monoclonal antibody (M02), clone M2.
Lane 1: HBG1 transfected lysate (Predicted MW: 16.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (41.91 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant HBG1.
Immunogen
HBG1 (AAH10913, 1 a.a. ~ 147 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAVMGNPKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVASALSSRYH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (74)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (41.91 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of HBG1 expression in transfected 293T cell line by HBG1 monoclonal antibody (M02), clone M2.
Lane 1: HBG1 transfected lysate (Predicted MW: 16.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — HBG1
Entrez GeneID
3047GeneBank Accession#
BC010913Protein Accession#
AAH10913Gene Name
HBG1
Gene Alias
HBGA, HBGR, HSGGL1, PRO2979
Gene Description
hemoglobin, gamma A
Omim ID
142200Gene Ontology
HyperlinkGene Summary
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq
Other Designations
A-gamma globin|gamma A hemoglobin|gamma globin|hemoglobin gamma-a chain|hemoglobin, gamma, regulator of
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Interactome
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Disease
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