HBB polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant HBB.
Immunogen
HBB (AAH07075, 38 a.a. ~ 147 a.a) partial recombinant protein with GST tag.
Sequence
WTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALPHKYH
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — HBB
Entrez GeneID
3043GeneBank Accession#
BC007075Protein Accession#
AAH07075Gene Name
HBB
Gene Alias
CD113t-C
Gene Description
hemoglobin, beta
Gene Ontology
HyperlinkGene Summary
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq
Other Designations
beta globin|beta globin chain|hemoglobin beta chain
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Interactome
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Disease
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Publication Reference
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Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3' end of human genes.
Martins SB, Rino J, Carvalho T, Carvalho C, Yoshida M, Klose JM, de Almeida SF, Carmo-Fonseca M.
Nature Structural & Molecular Biology 2011 Sep; 18(10):1115.
Application:WB, Human, U-2 OS cells.
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Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3' end of human genes.
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