GUCY1A3 monoclonal antibody (M01), clone 2H1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GUCY1A3.
Immunogen
GUCY1A3 (AAH28384, 41 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KATMPICQDIPEKNIQESLPQRKTSRSRVYLHTLAESICKLIFPEFERLNVALQRTLAKHKIKESRKSLEREDFEKTIAEQAVAAGVPVEVIKESLGEEV
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GUCY1A3 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — GUCY1A3
Entrez GeneID
2982GeneBank Accession#
BC028384Protein Accession#
AAH28384Gene Name
GUCY1A3
Gene Alias
GC-SA3, GUC1A3, GUCA3, GUCSA3, GUCY1A1
Gene Description
guanylate cyclase 1, soluble, alpha 3
Omim ID
139396Gene Ontology
HyperlinkGene Summary
Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit, such as alpha-1 (GUCY1A3), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM
Other Designations
GC-S-alpha-1|soluble guanylate cyclase large subunit
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Interactome
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Pathway
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