GUCY1A2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human GUCY1A2 partial ORF ( NP_000846, 296 a.a. - 401 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
CENTNIMKNLPQGTSQVPADLRISINTFCRAFPFHLMFDPSMSVLQLGEGLRKQLRCDTHKVLKFEDCFEIVSPKVNATFERVLLRLSTPFVIRTKPEASGSENKD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.4
Interspecies Antigen Sequence
Mouse (85); Rat (87)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GUCY1A2
Entrez GeneID
2977GeneBank Accession#
NM_000855Protein Accession#
NP_000846Gene Name
GUCY1A2
Gene Alias
GC-SA2, GUC1A2
Gene Description
guanylate cyclase 1, soluble, alpha 2
Omim ID
601244Gene Ontology
HyperlinkGene Summary
Soluble guanylyl (or guanylate) cyclases are heterodimeric enzymes consisting of an alpha subunit, such as alpha-2 (GUCY1A2), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), which are activated by nitric oxide (NO) and which catalyze conversion of GTP to 3-prime, 5-prime-cyclic GMP and pyrophosphate (Harteneck et al., 1991 [PubMed 1683630]).[supplied by OMIM
Other Designations
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