GTF3A monoclonal antibody (M07), clone 3F7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GTF3A.
Immunogen
GTF3A (NP_002088, 185 a.a. ~ 274 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NQQKQYICSFEDCKKTFKKHQQLKIHQCQNTNEPLFKCTQEGCGKHFASPSKLKRHAKAHEGYVCQKGCSFVAKTWTELLKHVRETHKEE
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GTF3A is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — GTF3A
Entrez GeneID
2971GeneBank Accession#
NM_002097Protein Accession#
NP_002088Gene Name
GTF3A
Gene Alias
AP2, TFIIIA
Gene Description
general transcription factor IIIA
Omim ID
600860Gene Ontology
HyperlinkGene Summary
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq
Other Designations
transcription factor IIIA
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