GTF2B (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human GTF2B full-length ORF ( AAH20597, 1 a.a. - 316 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MASTSRLDALPRVTCPNHPDAILVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRVNLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPTDFKFDTPVDKLPQL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
60.5
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GTF2B
Entrez GeneID
2959GeneBank Accession#
BC020597Protein Accession#
AAH20597Gene Name
GTF2B
Gene Alias
TF2B, TFIIB
Gene Description
general transcription factor IIB
Omim ID
189963Gene Ontology
HyperlinkGene Summary
This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq
Other Designations
OTTHUMP00000012347|OTTHUMP00000058838|RNA polymerase II transcription factor IIB
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Interactome
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Pathway
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