GTF2B rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human GTF2B peptide using ARM Technology.
Immunogen
A synthetic peptide of human GTF2B is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human GTF2B peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — GTF2B
Entrez GeneID
2959GeneBank Accession#
GTF2BGene Name
GTF2B
Gene Alias
TF2B, TFIIB
Gene Description
general transcription factor IIB
Omim ID
189963Gene Ontology
HyperlinkGene Summary
This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq
Other Designations
OTTHUMP00000012347|OTTHUMP00000058838|RNA polymerase II transcription factor IIB
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Pathway
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