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Last updated: 2017/12/10

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MSH6 Pre-design Chimera RNAi

  • Catalog # : H00002956-R01
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  • Specification
  • Product Description:
  • Homo sapiens mutS homolog 6 (E. coli) (MSH6), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000179
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 2956
  • Gene Name:
  • MSH6
  • Gene Alias:
  • GTBP,HNPCC5,HSAP
  • Gene Description:
  • mutS homolog 6 (E. coli)
  • Gene Summary:
  • This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq
  • Other Designations:
  • G/T mismatch-binding protein,mutS homolog 6,sperm-associated protein
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