GSS monoclonal antibody (M03), clone 4B6
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More Files
- More Functions
Western Blot (Cell lysate)
GSS monoclonal antibody (M03), clone 4B6-2C7. Western Blot analysis of GSS expression in NSO.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to GSS on formalin-fixed paraffin-embedded human colon tissue. [antibody concentration 1 ~ 10 ug/ml]
Western Blot detection against Immunogen (80 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant GSS.
Immunogen
GSS recombinant protein.
Sequence
MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQRSADGSPALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKILSNNPSKGLALGIAKAWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFEDISEKGSLDQDRRLF
Host
Mouse
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (89); Rat (88)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (80 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
GSS monoclonal antibody (M03), clone 4B6-2C7. Western Blot analysis of GSS expression in NSO.Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to GSS on formalin-fixed paraffin-embedded human colon tissue. [antibody concentration 1 ~ 10 ug/ml]ELISA
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Gene Info — GSS
Entrez GeneID
2937GeneBank Accession#
-Protein Accession#
-Gene Name
GSS
Gene Alias
GSHS, MGC14098
Gene Description
glutathione synthetase
Gene Ontology
HyperlinkGene Summary
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq
Other Designations
GSH synthetase|OTTHUMP00000030711|glutathione synthase
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Interactome
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Pathway
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Disease
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