GSN polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant GSN.
Immunogen
GSN (AAH26033, 673 a.a. ~ 782 a.a) partial recombinant protein with GST tag.
Sequence
SNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVDPLDRAMAELAA
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — GSN
Entrez GeneID
2934GeneBank Accession#
BC026033Protein Accession#
AAH26033Gene Name
GSN
Gene Alias
DKFZp313L0718
Gene Description
gelsolin (amyloidosis, Finnish type)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000022011|OTTHUMP00000162202|gelsolin
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Interactome
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Pathway
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Disease
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Publication Reference
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Proteomic profiling of human colon cancer cells treated with the histone deacetylase inhibitor belinostat.
Beck HC, Petersen J, Nielsen SJ, Morszeck C, Jensen PB, Sehested M, Grauslund M.
Electrophoresis 2010 Aug; 31(16):2714.
Application:WB, Human, HCT-116 cells.
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Proteomic profiling of human colon cancer cells treated with the histone deacetylase inhibitor belinostat.
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