PDIA3 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
PDIA3 MaxPab polyclonal antibody. Western Blot analysis of PDIA3 expression in human stomach.
Western Blot (Cell lysate)
PDIA3 MaxPab polyclonal antibody. Western Blot analysis of PDIA3 expression in A-431.
Western Blot (Transfected lysate)
Western Blot analysis of PDIA3 expression in transfected 293T cell line (H00002923-T01) by PDIA3 MaxPab polyclonal antibody.
Lane 1: PDIA3 transfected lysate(55.55 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PDIA3 protein.
Immunogen
PDIA3 (NP_005304.3, 1 a.a. ~ 505 a.a) full-length human protein.
Sequence
MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENIFGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PDIA3 MaxPab polyclonal antibody. Western Blot analysis of PDIA3 expression in human stomach.Western Blot (Cell lysate)
PDIA3 MaxPab polyclonal antibody. Western Blot analysis of PDIA3 expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of PDIA3 expression in transfected 293T cell line (H00002923-T01) by PDIA3 MaxPab polyclonal antibody.
Lane 1: PDIA3 transfected lysate(55.55 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PDIA3
Entrez GeneID
2923GeneBank Accession#
NM_005313.4Protein Accession#
NP_005304.3Gene Name
PDIA3
Gene Alias
ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC
Gene Description
protein disulfide isomerase family A, member 3
Omim ID
602046Gene Ontology
HyperlinkGene Summary
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. [provided by RefSeq
Other Designations
58 kDa microsomal protein|OTTHUMP00000041709|endoplasmic reticulum P58|glucose regulated protein, 58kDa|phospholipase C-alpha|protein disulfide isomerase-associated 3|protein disulfide-isomerase A3
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Interactome
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Pathway
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Disease
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Publication Reference
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JMJD8 is a novel endoplasmic reticulum protein with a JmjC domain.
Yeo KS, Tan MC, Lim YY, Ea CK.
Scientific Reports 2017 Nov; 7(1):15407.
Application：WB-Tr, Human, HEK 293T cells.
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Identification of novel downstream targets of platelet glycoprotein VI activation by differential proteome analysis: implications for thrombus formation.
Schulz C, Leuschen NV, Frohlich T, Lorenz M, Pfeiler S, Gleissner CA, Kremmer E, Kessler M, Khandoga AG, Engelmann B, Ley K, Massberg S, Arnold GJ.
Blood 2010 May; 115(20):4102.
Application：WB-Ce, Human, Human platelets.
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JMJD8 is a novel endoplasmic reticulum protein with a JmjC domain.
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