GRP DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human GRP DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSSVSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFKDVGSKGKVGRLSAPGSQREGRNPQLNQQ
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — GRP
Entrez GeneID
2922GeneBank Accession#
BC004488Protein Accession#
AAH04488Gene Name
GRP
Gene Alias
BN, GRP-10, preproGRP, proGRP
Gene Description
gastrin-releasing peptide
Omim ID
137260Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
bombesin|neuromedin C|pre-progastrin releasing peptide
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Interactome
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Pathway
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Disease
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