GRLF1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human GRLF1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MEATSRSVHGDVGEVGHFEGMAVCWCPRRGILPGLR
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — GRLF1
Entrez GeneID
2909GeneBank Accession#
ENST00000355222Protein Accession#
ENSP00000347361Gene Name
GRLF1
Gene Alias
GRF-1, KIAA1722, MGC10745, P190-A, P190A, p190RhoGAP
Gene Description
glucocorticoid receptor DNA binding factor 1
Omim ID
605277Gene Ontology
HyperlinkGene Summary
The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq
Other Designations
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Interactome
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