GRIN2B (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human GRIN2B partial ORF ( NP_000825, 127 a.a. - 236 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
HGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQLKKLQSPIILLYCTKEE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GRIN2B
Entrez GeneID
2904GeneBank Accession#
NM_000834Protein Accession#
NP_000825Gene Name
GRIN2B
Gene Alias
MGC142178, MGC142180, NMDAR2B, NR2B, hNR3
Gene Description
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Omim ID
138252Gene Ontology
HyperlinkGene Summary
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq
Other Designations
N-methyl-D-aspartate receptor subunit 2B|glutamate receptor subunit epsilon-2
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Interactome
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Disease
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