GRIK2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GRIK2 protein.
Immunogen
GRIK2 (AAH37954.1, 1 a.a. ~ 353 a.a) full-length human protein.
Sequence
MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTMEFHSCCPGWSAMARSHLTAASASWVQAILLPQPPE
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of GRIK2 expression in transfected 293T cell line (H00002898-T03) by GRIK2 MaxPab polyclonal antibody.
Lane 1: GRIK2 transfected lysate(38.94 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GRIK2
Entrez GeneID
2898GeneBank Accession#
BC037954Protein Accession#
AAH37954.1Gene Name
GRIK2
Gene Alias
EAA4, GLR6, GLUK6, GLUR6, MGC74427, MRT6
Gene Description
glutamate receptor, ionotropic, kainate 2
Gene Ontology
HyperlinkGene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq
Other Designations
OTTHUMP00000017949|bA487F5.1|excitatory amino acid receptor 4|glutamate receptor 6
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