GRIK1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human GRIK1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — GRIK1
Entrez GeneID
2897GeneBank Accession#
BC152727.1Protein Accession#
AAI52728.1Gene Name
GRIK1
Gene Alias
EAA3, EEA3, GLR5, GLUR5
Gene Description
glutamate receptor, ionotropic, kainate 1
Omim ID
138245Gene Ontology
HyperlinkGene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000096569|excitatory amino acid receptor 3|glutamate receptor 5
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Interactome
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Pathway
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Disease
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