Products

Western Blot (Transfected lysate)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

GRIK1

Gene Alias

EAA3, EEA3, GLR5, GLUR5

Gene Description

glutamate receptor, ionotropic, kainate 1

Omim ID

Gene Ontology

Gene Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq

Other Designations

OTTHUMP00000096569|excitatory amino acid receptor 3|glutamate receptor 5