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GRN 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00002896-T01
  • Visit Frequency :
  • Countries :
  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-GRN full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 65.34
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-GRN antibody (H00002896-B01) by Western Blots.
    Western Blot
    QC Testing of H00002896-T01
    Lane 1: GRN transfected lysate ( 63.5 KDa)
    Lane 2: Non-transfected lysate.
    SDS-PAGE Gel
    QC Testing of H00002896-T01
    GRN transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 2896
  • Gene Name:
  • GRN
  • Gene Alias:
  • Gene Description:
  • granulin
  • Gene Summary:
  • Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq
  • Other Designations:
  • PC cell-derived growth factor,acrogranin,granulin-epithelin,proepithelin,progranulin
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