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Last updated: 2016/10/16

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GRID2 Pre-design Chimera RNAi

  • Catalog # : H00002895-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens glutamate receptor, ionotropic, delta 2 (GRID2), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001510
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 2895
  • Gene Name:
  • GRID2
  • Gene Alias:
  • MGC117022,MGC117023,MGC117024
  • Gene Description:
  • glutamate receptor, ionotropic, delta 2
  • Gene Summary:
  • Human glutamate receptor delta-2 (GRID2) is a relatively new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. GRID2 is a predicted 1,007 amino acid protein that shares 97% identity with the mouse homolog which is expressed selectively in cerebellar Purkinje cells. A point mutation in mouse GRID2, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This strongly suggests a role for GRID2 in neuronal apoptotic death. [provided by RefSeq
  • Other Designations:
  • GluR-delta-2,OTTHUMP00000161600
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