GRB10 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-GRB10 full-length
Host
Human
Theoretical MW (kDa)
59.07
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-GRB10 antibody (H00002887-B02) by Western Blots.
SDS-PAGE Gel
GRB10 transfected lysate.
Western Blot
Lane 1: GRB10 transfected lysate ( 59.07 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — GRB10
Entrez GeneID
2887GeneBank Accession#
NM_001001550Protein Accession#
NP_001001550Gene Name
GRB10
Gene Alias
GRB-IR, Grb-10, IRBP, KIAA0207, MEG1, RSS
Gene Description
growth factor receptor-bound protein 10
Omim ID
601523Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
GRB10 adaptor protein|insulin receptor-binding protein Grb-IR|maternally expressed gene 1
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Interactome
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Disease
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