GRB2 monoclonal antibody (M01A), clone 4C6-H6
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant GRB2.
Immunogen
GRB2 (AAH00631, 1 a.a. ~ 217 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (100)
Isotype
IgM kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (49.61 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
GRB2 monoclonal antibody (M01A), clone 4C6-H6 Western Blot analysis of GRB2 expression in HL-60 ( Cat # L014V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — GRB2
Entrez GeneID
2885GeneBank Accession#
BC000631Protein Accession#
AAH00631Gene Name
GRB2
Gene Alias
ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084
Gene Description
growth factor receptor-bound protein 2
Omim ID
108355Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
HT027|OTTHUMP00000166096|OTTHUMP00000166097|OTTHUMP00000166098|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3
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Interactome
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Disease
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