GPX5 monoclonal antibody (M02), clone 3B9
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More Files
- More Functions
Immunoprecipitation
Immunoprecipitation of GPX5 transfected lysate using anti-GPX5 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with GPX5 MaxPab rabbit polyclonal antibody.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GPX5 is 1 ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GPX5.
Immunogen
GPX5 (NP_001500, 122 a.a. ~ 221 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIRWNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (74); Rat (75)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of GPX5 transfected lysate using anti-GPX5 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with GPX5 MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GPX5 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — GPX5
Entrez GeneID
2880GeneBank Accession#
NM_001509Protein Accession#
NP_001500Gene Name
GPX5
Gene Alias
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Gene Description
glutathione peroxidase 5 (epididymal androgen-related protein)
Omim ID
603435Gene Ontology
HyperlinkGene Summary
This gene belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike mRNAs for other characterized glutathione peroxidases, this mRNA does not contain a selenocysteine (UGA) codon. Thus, the encoded protein is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000017919|epididymal androgen-related protein|epididymal secretory glutathione peroxidase|glutathione peroxidase 5
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Pathway
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Disease
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