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GPX4 Pre-design Chimera RNAi

  • Catalog # : H00002879-R01
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  • Specification
  • Product Description:
  • Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002085
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 2879
  • Gene Name:
  • GPX4
  • Gene Alias:
  • MCSP,PHGPx,snGPx,snPHGPx
  • Gene Description:
  • glutathione peroxidase 4 (phospholipid hydroperoxidase)
  • Gene Summary:
  • Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq
  • Other Designations:
  • glutathione peroxidase 4,phospholipid hydroperoxidase,phospholipid hydroperoxide glutathione peroxidase, mitochondrial,sperm nucleus glutathione peroxidase
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