GPS2 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (37 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant GPS2.
Immunogen
GPS2 (AAH13652, 228 a.a. ~ 327 a.a) partial recombinant protein with GST tag.
Sequence
QPYAVHGHFQPTQTGFLQPGGALSLQKQMEHANQQTGFSDSSSLRPMHPQALHPAPGLLASPQLPVQMQPAGKSGFAATSQPGPRLPFIQHSQNPRFYHK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — GPS2
Entrez GeneID
2874GeneBank Accession#
BC013652Protein Accession#
AAH13652Gene Name
GPS2
Gene Alias
AMF-1, MGC104294, MGC119287, MGC119288, MGC119289
Gene Description
G protein pathway suppressor 2
Omim ID
601935Gene Ontology
HyperlinkGene Summary
This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq
Other Designations
OTTHUMP00000128385|OTTHUMP00000163158
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