GRK4 monoclonal antibody (M01), clone 6D12
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GRK4 is approximately 0.3ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to GRK4 on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (37.73 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GRK4.
Immunogen
GRK4 (NP_892027, 36 a.a. ~ 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LPPVSQCSELRHSIEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPEIPPDVVTECRLGLKEENPSKKAFEE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (68); Rat (64)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GRK4 is approximately 0.3ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to GRK4 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — GRK4
Entrez GeneID
2868GeneBank Accession#
NM_182982Protein Accession#
NP_892027Gene Name
GRK4
Gene Alias
GPRK2L, GPRK4, GRK4a, IT11
Gene Description
G protein-coupled receptor kinase 4
Omim ID
137026Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. [provided by RefSeq
Other Designations
G protein-coupled receptor kinase 2-like|G-protein coupled receptor kinase 4
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Interactome
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Pathway
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Disease
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